1962 - A sick infant, a disabled car on a Chicago freeway, and a January blizzard prompted Henry B. (Pete) Kreer to envision using CB radio to get help in such emergencies. By April, REACT was founded, with Hallicrafter Radio as its first sponsor and Kreer as its Executive Director.

1967 - REACT approached FCC for a designated CB Emergency Channel.

1969 - REACT gained General Motors Research Labs as its new sponsor.

1970 - CB-9 was designated the 'Emergency and Travellers' Assistance Channel' by the FCC. The Ohio REACT Network was created. It worked with Ohio State Police to demonstrate how CB-9 could enhance highway safety. It later became the first REACT Council.
REACT signed its first MOU (Memorandum of Understanding) with the American Red Cross.

1973 - REACT's Pete Kreer and Gerry Reese were interviewed on the NBC 'Today' show about the potential for highway safety of CB radio.

1975 - REACT became an Illinois not-for-profit corporation.

1976 - REACT held its first convention in Deerfield, IL. REACT participated in the White House Conference on CB Radio.

1977 - REACT launched its highway Safety Break program in co-operation with the American Trucking Associations. REACT developed the NEAR (National Emergency Aid Radio) safety program for the U.S. government.

1978 - REACT signed an MOU with Special Olympics.

1984 - REACT assisted in introducing FRS (Family Radio Service).

1986 -'REACT Month' was observed for the first time.

1988 - REACT developed its 'Team Topics' newsletter for Teams.
REACT introduced the CB-9 road sign to advise travellers of monitoring.

1991 - REACT published the first in a series of 'Team Training Modules' to advance its monitors' skills.

1995 - REACT HQ established its first website on the internet.
Rose City Windsor REACT, Ontario, launched the first REACT Team website.

1998 - REACT moved its Headquarters from Wichita, KS to the DC area.